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Technical Information - Click here for PDF
Vial Finish Specifications
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Standard
Screw Thread Finish
"T"
= Outer diameter of the thread
"E" = Inside diameter of the thread
"ID" = Inside diameter
"S" = Start of thread
"H" = Distance from top of finish to shoulder for
closure clearance |
Standard
Crimp Seal Finish
"T"
= Outer diameter of seal
"E" = Crimp tool and robotic arm clearance
"ID" = Inside diameter
"A" = Crimp seal thickness
"H" = Distance from top to shoulder for crimp and
robotic arm clearance |
Screw Thread Finishes
GPI refers to the "Glass Packaging Institute"
The
GPI is responsible for establishing and issuing standards
for the types and finishes produced by American glass
manufacturers.
For
example, an 8-425 neck finish is approximately 8mm in
diameter across the outside of the threads.
The
425 represents the finish (style of thread). |
Typical GPI finishes found in the chromatography
field are as follows:
8-425
Closure - Varian, Shimadzu
10-425 Closure - Waters Alliance 2690
13-425 Closure - Waters 48 position WISP™, Shimadzu
Note:
9mm thread finish does not appear in the GPI finishes.
It is not a standard finish. The 9mm closure and vial are
used with Agilent equipment. |
Glass
Technical Information
Terminology
Borosilicate - A glass that is high in silicate and having at least
5% boron oxide.
Linear
Coefficient of Expansion - Fractional change
in length of glass per degree change in temperature.
Strain
Point - Maximum temperature to which glass should
be heated during use.
Types
of Glass
USP
Type - Pharmaceutical glass containers can be
classified as USP Type I, II, III or NP. |
Type
I - Borosilicate glass represents the least reactive
glass.
Type I glass has the least pH shift. (Lowest leaching characteristics)
Coefficient
of Expansion = 33 or 51 for Clear and 51 for Amber
Type
II - is de-alkalized soda lime glass with higher
levels of sodium hydroxide and calcium oxide.
Type
III - soda lime glass - cannot be autoclaved.
Type
NP - general purpose soda-lime glass used where
chemical durability and heat shock are not factors.
Coefficient
of Expansion = 92 |
GLASS
PROPERTIES
| Color |
Clear |
Amber |
| Linear
Coefficient of Expansion |
33 |
51 |
| Strain
Point (Degrees Celsius) |
515 |
535 |
| USP
Class Type |
Type
1 |
Type
1 |
| Light
Protection |
No |
Yes |
PLASTIC
PROPERTIES
For a Comprehensive Listing of the Chemical Resistance to Membranes and Plate Matrices, download this PDF
| Type
of Plastic |
LDPE |
HDPE |
PP |
PMP |
PS |
| Maximum
use temperature, C/F |
80°C/176°F |
120°C/248°F |
135°C/275°F |
175°C/347°F |
90°C/194°F |
| Transparency |
Translucent |
Translucent |
Translucent |
Clear |
Clear |
| Sterilization |
|
|
|
|
|
Autoclaving |
No |
No |
Yes |
Yes |
No |
Disinfectants |
Yes |
Yes |
Yes |
Yes |
No |
Dry
Heat |
No |
No |
No |
Yes |
No |
Radiation |
Yes |
Yes |
No* |
No |
Yes |
| Specific
Gravity |
0.92 |
0.95 |
0.90 |
0.83 |
1.05 |
| Flexibility** |
Good |
Rigid |
Rigid |
Rigid |
Rigid |
Note: Chart is general guideline only.
PP* = Some radiation resistant polypropylene resins available.
**Flexibility - Depends on thickness.
SEPTA MATERIALS
| Material |
Temp. Range |
Compatibility |
Incompatibility |
Resealability |
Polypropylene (PP)
(Used in molded caps with a thin penetration point, such as snap caps or snap plugs.)
|
0°C - 135°C |
Acetone, ethyl acetate, methanol, isobutyl alcohol, methanol, and methyl ethyl ketone |
cyclohexane, ethers, dichlorobenzene, pentanes, methylene chloride, and trichlorobenzene |
For one time use only, not resealable. Not recommended for lengthy sample storage. |
| Polyethylene (PE) Used in molded caps with a thin penetration point, such as snap caps or snap plugs.) |
Maximum temperature use is 120°C | Acids, alcohol, and bases |
benzene, chlorobenzene, acetic anhydride |
For one time use only, not resealable. Easily penetrated by syringe needles. |
| Polytetrafluoroethylene (PTFE) |
-265°C - 250°C
| Aliphatic hydrocarbons, aromatic hydrocarbons, alcohols, oils, gasoline, animal and vegetable oils, acids, and alkalies |
None |
For one time use only; not resealable. Not recommended for lengthy sample storage. |
PTFE/Butyl and
Molded PTFE/Butyl |
-40°C - 120°C |
Alcohols, animal and vegetable oils, acids |
Aliphatic hydrocarbons, aromatic hydrocarbons, oil, gasoline |
Good
|
PTFE/Red Rubber |
-40°C - 110°C |
ACN, acetone, DMF, alcohols, Diethylamine, DMSO, Phenol |
Aromatics, hydrocarbons, carbon disulfide |
Not recommended for mulitple injections or holding sample for future analysis. |
| PTFE/Silicone |
-40°C - 200°C |
Alcohols, acetone, ether, DMF, DMSO |
ACN, THF, chloroform, pyridine, benzene, toluene, hexane, heptanes |
Above average |
| PTFE/Silicone/PTFE |
-40°C - 200°C |
Alcohols, acetone, ether, DMF, DMSO |
Chlorosilanes, ACN, THF, chloroform, pyridine, benzene, toluene, hexane, heptanes |
Above average |
| Flouroelastomers (Viton*) |
-23°C - 204°C |
Chlorinated
solvents, benezene,
toluene, alcohols, hexane, heptane |
DMF,
DMSO, ACN, THF, pyridine
dioxane, methanol, acetone
|
Very good |
- Graduated Vial™, R.A.M. Vial™, Scallop Pack™, Snap Rack™, Snap Ring™ Vial, Snap Top Cap™, Top Seal™ Closure and Multi-Tier™ are trademarks of J.G. Finneran Associates, Inc.
- Capsule Holders™, Poly Crimp™ Seal, Snap Seal™ Vial, Top Hat™, Top Spring™ and 96-Well Multi-Tier™ MTP System are patented by J.G. Finneran Associates, Inc.
- TPX™ is a trademark of Imperial Chemical Industries, Ltd.
- Viton® is a registered trademark of E.I. DuPont.
- Waters WISP™ is a trademark of Waters Corporation.
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